Every chemist can remember a special science laboratory activity they enjoyed doing. Often, it is the laboratory portion of a science course that provides some motivation to seek a career in science or engineering. AP Chemistry Guided-Inquiry Experiments: Applying the Science Practices provides 16 laboratory activities developed and classroom tested to incorporate best practices that support maximum student learning of chemistry content and skills. These best practices include an inquiry model of instruction, which differs substantially from the traditional model of laboratory learning. This chapter is a part of the excellent book that you can download for free. It provides a brief introduction to inquiry in the AP Chemistry lab.